Lek Bensedin rastvor za injekciju/infuziju sadrži propilenglikol i etanol (videti odeljak 4.four). Evropska agencija za lekove (EMA) je izdala preporuke za dnevne limite izloženosti ekscipijensu propilenglikolu u sledećim pedijatrijskim populacijama:
Benzodiazepini nisu indikovani kod pacijenata sa teškim oštećenjem funkcije jetre, s obzirom na to da mogu da izazovu nastanak encefalopatije. Kod pacijenata sa hroničnim oboljenjem jetre, može biti neophodno smanjiti dozu leka.
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Should you have considerations about dependency, speak to your Health care company. They can help you by recommending a therapy timeline, decreasing your dosage, or switching you to a medication having a lessen potential for dependency.
Zbog toga je Evropska agencija za lekove za pomoćnu supstancu propilenglikol definisala granicu od fifty mg/kg/dan (što odgovara 0,625 mg/kg/dan po dozi leka Bensedin, rastvor za injekciju/infuziju) kod pacijenata s oštećenjem funkcije jetre ili bubrega.
Ne smete koristiti lek Bensedin, rastvor za injekciju/infuziju posle isteka roka upotrebe naznačenog na spoljašnjem pakovanju nakon „Važi do“. Datum isteka roka upotrebe se odnosi na poslednji dan navedenog meseca.
The power and length of action of benzodiazepines are essential in what situations they take care of. Short-time period or unexpected emergency problems normally advantage the use of stronger, limited-performing benzodiazepines.
Do not maintain out-of-day or unwelcome medicines. Take them to your neighborhood pharmacy that may get rid of them in your case.
If any with the side effects come to be severe, or for those who discover any facet effect not listed In this particular leaflet, make sure you convey to your health care provider or pharmacist.
Usporen metabolizam diazepama dovodi do produženja poluvremena eliminacije i povećanja koncentracije diazepama u plazmi. Usporena je eliminacija N-demetil metabolita diazepama, što može značajno pojačati sedativni efekat. Povećan je rizik od inhibicije CNS, npr. sedacije.
Don’t choose prospects. If there’s even the slightest probability that someone spiked your consume, don’t drink it. If you think click here you drank from the spiked drink, get assist without delay. In case you’re with somebody and you think they drank from the spiked drink, get help for them promptly.
These remedies deal with conditions depending on which result they induce. Even though there are actually different kinds because they have distinctive Major effects, there’s a great deal of overlap concerning them. For instance, most benzodiazepines Use a sedative result In combination with their primary influence.
When you are taking some other medicines. This features any medicines you might be getting which are offered to purchase without a prescription, and also herbal and complementary medicines.
Dejstvo se može uočiti odmah nakon započinjanja terapije i može trajati nekoliko dana nakon galenika bensedin prestanka terapije zbog dugog poluvremena eliminacije diazepama.